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J. Comput. Sci. Eng.
Vol. 50 (2020) 1166-1182 |
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Effect of nanoscale VC precipitate on mechanical properties of microalloyed steel researched by finite element model |
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Wu Zhaoyu |
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J. Comput. Sci. Eng. 50 (2020) 1166-1178！Published
20 November 2020 |
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Abstract:
A finite element calculation has been used to study the effect of nanoscalesizeof VC precipitate on mechanical properties ofhigh strength low alloy steels (HSLA). Though comparing the modes of real structure with finite element model, it has been found that the strength increases with the decrease of the precipitatesizes, whilethe change of ductility is instead. It also shows that the elastic and plastic anisotropy areinduced by VC precipitates generated in tensile deformation process. There is high equivalent stress and no plastic deformation in VC precipitates. Furthermore, the interaction of dislocation and VC precipitates is investigated by analyzing the stress distribution in VC precipitates, which indicates thatwhen the precipitates size is10 ~15 nm can more effectively improve the mechanical properties of the microalloyed steels. |
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Keywords:
Nanoscale VC precipitates, Finite element method, Dislocation, Mechanical properties , Micro alloyed steel
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Evaluation the effect on ulcerative colitis of traditional Chinese medicine formula ya dan zi oil oral emulsion |
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Wei-ding Wang, Zi-cong Wu, Yi-fei Wang, Zhi-ping Wang |
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J. Comput. Sci. Eng. 50 (2020) 1179-1182！Published
20 November 2020 |
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Abstract:
Ulcerative colitis(UC) is a chronic inflammatory disease affecting the colon, and its incidence is rising worldwide. Patients with ulcerative colitis have mucosal inflammation starting in the rectum that can extend continuously to proximal segments of the colon. Ulcerative colitis usually presents with bloody diarrhoea and is diagnosed by colonoscopy and histological findings. Ya dan zi oil oral emulsion(YDZ),a traditional Chinese medicine formula, composed of bruceae fructus(ya dan zi), is widely used as a clinically medication formula for its efficiency in cancers. But the underlying mechanisms by which it exerts therapeutic function of UC has not been thoroughly studied. In this study, acute ulcerative colitis was induced by oral administration of 2.5% dextran sodium sulfate for 7 days in drinking water, YDZ (12.0ml/kg body weight) decreased disease activity index and improved colon length at a certain degree, but compared with positive group(sulfasalazine) has no statistical significance.These results indicated that YDZ can hold protective effect on UC mice, but can not be used as a pharmaceutical preparations for UC treatments pontentionally. |
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Keywords:Ya dan zi oil oral emulsion; Bruceae fructus; Ulcerative colitis
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